Aromatase polyclonal, anti-human, mouse, rat, bovine, dog, hamster, monkey, guinea pig, rabbit, sheep, goat, pig, horse, chicken, xenopus
€378.00
In stock
SKU
250549
Catalog Nr.: 250549
Size: 0.1 mg
Isotype: Mouse Ig
Applications: E, WB, IHC
Size: 0.1 mg
Isotype: Mouse Ig
Applications: E, WB, IHC
Protein Family: Cytochrome P450, Enzymes, Hormones
Pathway and Disease: Lipid Metabolism, Endocrine System
Description:
Aromatase (cytochrome P450 19A1) catalyzes the formation of aromatic C18 estrogens from C19 androgens. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This aromatase localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis, three successive hydroxylations of the A ring of androgens.
Alternate Names: Cytochrome P450 19A1, CYPXIX, Aromatase, Estrogen synthetase, P-450AROM, CYP19A1, ARO1, CYAR, CYP19
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:200-1:500
Accession No.: P11511
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human Aromatase.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Product Citations:
Sittadjody S. et al. 2013. Biomaterials. 34(10): 2412-20. PMID #23274068.
Pathway and Disease: Lipid Metabolism, Endocrine System
Description:
Aromatase (cytochrome P450 19A1) catalyzes the formation of aromatic C18 estrogens from C19 androgens. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This aromatase localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis, three successive hydroxylations of the A ring of androgens.
Alternate Names: Cytochrome P450 19A1, CYPXIX, Aromatase, Estrogen synthetase, P-450AROM, CYP19A1, ARO1, CYAR, CYP19
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:200-1:500
Accession No.: P11511
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human Aromatase.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Product Citations:
Sittadjody S. et al. 2013. Biomaterials. 34(10): 2412-20. PMID #23274068.
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