ATF-1 polyclonal, anti-human, mouse, rat, chicken, dog, pig, bovine
€378.00
In stock
SKU
251171
Catalog Nr.: 251171
Size: 0.1 mg
Isotype: Rabbit Ig
Applications: E, WB, IHC, IP
Size: 0.1 mg
Isotype: Rabbit Ig
Applications: E, WB, IHC, IP
Protein Family: Transcription Factors
Pathway and Disease: Infectious Diseases
Description:
Activating transcription factor 1 (ATF-1) is a protein that binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. ATF-1 binds to the Tax-responsive element (TRE) of HTLV-I. ATF-1 mediates PKA-induced stimulation of CRE-reporter genes. Defects in ATF-1 are linked to angiomatoid fibrous histiocytoma (AFH). AFH is a distinct variant of malignant fibrous histiocytoma that typically occurs in children and adolescents and is manifest by nodular subcutaneous growth.
Alternate Names: ATF-1, Activating Transcription Factor-1, ATF1, Cyclic AMP-dependent transcription factor ATF-1, cAMP-dependent transcription factor ATF-1, Activating transcription factor 1, Protein TREB36
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500; IP: 1:100-1:500
Accession No.: P18846
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human ATF-1.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by immunogen affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Pathway and Disease: Infectious Diseases
Description:
Activating transcription factor 1 (ATF-1) is a protein that binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. ATF-1 binds to the Tax-responsive element (TRE) of HTLV-I. ATF-1 mediates PKA-induced stimulation of CRE-reporter genes. Defects in ATF-1 are linked to angiomatoid fibrous histiocytoma (AFH). AFH is a distinct variant of malignant fibrous histiocytoma that typically occurs in children and adolescents and is manifest by nodular subcutaneous growth.
Alternate Names: ATF-1, Activating Transcription Factor-1, ATF1, Cyclic AMP-dependent transcription factor ATF-1, cAMP-dependent transcription factor ATF-1, Activating transcription factor 1, Protein TREB36
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500; IP: 1:100-1:500
Accession No.: P18846
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human ATF-1.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by immunogen affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
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