ATF-2 polyclonal, anti-human, mouse, rat, dog, horse, chicken

Protein Family: Transcription Factors

Pathway and Disease: Signal Transduction, Transcription

Description:
Activating transcription factor 2 (ATF-2) is a transcriptional activator, probably constitutive, which binds to the cAMP-responsive element (CRE) consensus sequence: 5'-GTGACGT[AC][AG]-3', a sequence present in many viral and cellular promoters.ATF-2 binds DNA as a dimer and can form a homodimer in the absence of DNA. ATF-2 can form a heterodimer with JUN, and interacts with SMAD3 and SMAD4.

Alternate Names: ATF-2, Activating Transcription Factor 2, ATF2, Cyclic AMP-dependent transcription factor ATF-2, cAMP-dependent transcription factor ATF-2, Activating transcription factor 2, cAMP response element-binding protein CRE-BP1, HB16, Cyclic AMP-responsive element-binding protein 2, cAMP-responsive element-binding protein 2, CREB-2, CREB2, CREBP1

Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500; IP: 1:100-1:500

Accession No.: P15336

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human ATF-2.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.