ATF-4 polyclonal, anti-human, mouse, rat

Protein Family: Transcription Factors

Pathway and Disease: Signaling Molecules and Interaction, Endocrine System, Nervous and Sensory Systems, Cancers, Folding, Sorting and Degradation

Description:
Cyclic AMP-dependent transcription factor ATF-4 (ATF-4) is a transcriptional activator that binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. ATF-4 binds to a Tax-responsive enhancer element in the long terminal repeat of HTLV-I.

Alternate Names: Cyclic AMP-dependent transcription factor ATF-4, cAMP-dependent transcription factor ATF-4, Activating transcription factor 4, Tax-responsive enhancer element-binding protein 67, TaxREB67, DNA-binding protein TAXREB67, Cyclic AMP-responsive element-binding protein 2, cAMP-responsive element-binding protein 2, CREB-2, ATF4, CREB2, TXREB

Application Notes: E: 1:20,000-1:80,000; WB: 1:200-1:1,000; IHC: 1:100-1:500

Accession No.: P18848

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human ATF-4.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.