ATF2 Antibody (T53) Blocking Peptide
€293.00
In stock
SKU
AC-BP6280f
Background:
ATF2 is a transcription factor that is a member of the leucine zipper family of DNA binding proteins. It binds to the cAMP-responsive element (CRE), an octameric palindrome. This protein forms a homodimer or heterodimer with c-Jun and stimulates CRE-dependent transcription. It is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components.
Other Names: Cyclic AMP-dependent transcription factor ATF-2, cAMP-dependent transcription factor ATF-2, Activating transcription factor 2, Cyclic AMP-responsive element-binding protein 2, CREB-2, cAMP-responsive element-binding protein 2, HB16, Histone acetyltransferase ATF2, cAMP response element-binding protein CRE-BP1, ATF2, CREB2, CREBP1
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP6280f was selected from the T53 region of human ATF2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Type: Synthetic peptide
Primary Accession: P15336
Gene ID: 1386
Gene Name: ATF2
Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Bio References:
Kravets, A., et al., J. Biol. Chem. 279(19):19916-19923 (2004).Hong, S., et al., J. Biol. Chem. 279(17):16996-17003 (2004).Averous, J., et al., J. Biol. Chem. 279(7):5288-5297 (2004).Berger, A.J., et al., Cancer Res. 63(23):8103-8107 (2003).Wen-Sheng, W., Oncogene 22(7):955-963 (2003).
ATF2 is a transcription factor that is a member of the leucine zipper family of DNA binding proteins. It binds to the cAMP-responsive element (CRE), an octameric palindrome. This protein forms a homodimer or heterodimer with c-Jun and stimulates CRE-dependent transcription. It is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components.
Other Names: Cyclic AMP-dependent transcription factor ATF-2, cAMP-dependent transcription factor ATF-2, Activating transcription factor 2, Cyclic AMP-responsive element-binding protein 2, CREB-2, cAMP-responsive element-binding protein 2, HB16, Histone acetyltransferase ATF2, cAMP response element-binding protein CRE-BP1, ATF2, CREB2, CREBP1
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP6280f was selected from the T53 region of human ATF2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Type: Synthetic peptide
Primary Accession: P15336
Gene ID: 1386
Gene Name: ATF2
Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Bio References:
Kravets, A., et al., J. Biol. Chem. 279(19):19916-19923 (2004).Hong, S., et al., J. Biol. Chem. 279(17):16996-17003 (2004).Averous, J., et al., J. Biol. Chem. 279(7):5288-5297 (2004).Berger, A.J., et al., Cancer Res. 63(23):8103-8107 (2003).Wen-Sheng, W., Oncogene 22(7):955-963 (2003).
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