ATG9A polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS71040
Background:
Atg9a (autophagy-related protein 9A), also known as APG9-like 1, is a 839 amino acid, multi-pass membrane protein that localizes to the pre-autophagosomal structure (PAS). Isolation membranes are suggested to originate from the PAS, enwrapping cytoplasmic components to form a double membrane autophagosome, which then fuses with the vacuole. Ubiquitously expressed in human adult tissues, Atg9a cycles between the Golgi and endosomes and, with the autophagosome-specific marker LC3, plays a critical role in starvation-induced autophagosome formation. Three isoforms of Atg9a exist as a result of alternative splicing events.
Alternative Name:
Autophagy-related protein 9A, APG9-like 1, mATG9, ATG9A, APG9L1
Application Dilution: WB: 1:500 - 1:2000
Specificity: ATG9A polyclonal antibody detects endogenous levels of ATG9A protein.
Immunogen:
Recombinant protein of human ATG9A.
MW: ~ 94 kDa
Swis Prot.: Q7Z3C6
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Atg9a (autophagy-related protein 9A), also known as APG9-like 1, is a 839 amino acid, multi-pass membrane protein that localizes to the pre-autophagosomal structure (PAS). Isolation membranes are suggested to originate from the PAS, enwrapping cytoplasmic components to form a double membrane autophagosome, which then fuses with the vacuole. Ubiquitously expressed in human adult tissues, Atg9a cycles between the Golgi and endosomes and, with the autophagosome-specific marker LC3, plays a critical role in starvation-induced autophagosome formation. Three isoforms of Atg9a exist as a result of alternative splicing events.
Alternative Name:
Autophagy-related protein 9A, APG9-like 1, mATG9, ATG9A, APG9L1
Application Dilution: WB: 1:500 - 1:2000
Specificity: ATG9A polyclonal antibody detects endogenous levels of ATG9A protein.
Immunogen:
Recombinant protein of human ATG9A.
MW: ~ 94 kDa
Swis Prot.: Q7Z3C6
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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