ATP11B polyclonal, anti-human, mouse
€396.00
In stock
SKU
254323
Catalog Nr.: 254323
Size: 0.1 mg
Isotype: Rabbit Ig
Applications: E, WB, ICC
Size: 0.1 mg
Isotype: Rabbit Ig
Applications: E, WB, ICC
Protein Family: Enzymes
Pathway and Disease: Signaling Molecules and Interaction
Description:
ATP11B is a widely expressed integral membrane ATPase and is thought to drive the transport of phospholipids across membranes. It has been suggested that ATP11B is hormonally regulated and plays a role in the subnuclear trafficking of transcription factors with RING motifs. While the exact molecule ATP11B transports is unknown, increased mRNA expression of the homologous ATP11A has been observed in cells resistant to anti-cancer drugs such as farnesyltransferase inhibitors (FTIs), suggesting that ATP11B may also play a role in cell survival under harsh conditions.
Alternate Names: ATP11B, ATPase class VI type 11B, ATPIF, ATPIR
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; ICC: 1:100-1:500
Accession No.: NP_055431
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within a 19 amino acid peptide near the amino terminus of human ATP11B.
Format: Each vial contains 0.1 ml IgG in PBS pH 7.4 with 0.02% sodium azide. Antibody was purified by immunogen affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Pathway and Disease: Signaling Molecules and Interaction
Description:
ATP11B is a widely expressed integral membrane ATPase and is thought to drive the transport of phospholipids across membranes. It has been suggested that ATP11B is hormonally regulated and plays a role in the subnuclear trafficking of transcription factors with RING motifs. While the exact molecule ATP11B transports is unknown, increased mRNA expression of the homologous ATP11A has been observed in cells resistant to anti-cancer drugs such as farnesyltransferase inhibitors (FTIs), suggesting that ATP11B may also play a role in cell survival under harsh conditions.
Alternate Names: ATP11B, ATPase class VI type 11B, ATPIF, ATPIR
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; ICC: 1:100-1:500
Accession No.: NP_055431
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within a 19 amino acid peptide near the amino terminus of human ATP11B.
Format: Each vial contains 0.1 ml IgG in PBS pH 7.4 with 0.02% sodium azide. Antibody was purified by immunogen affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
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