ATP7B polyclonal, anti-human, mouse
€388.00
In stock
SKU
BS7662
Background:
This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein functions as a monomer, exporting copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease (WD).
Alternative Name:
ATP7B, ATP7B_HUMAN, ATPase, Cu(2+) transporting, beta polypeptide, ATPase, Cu++ transporting, beta polypeptide, Copper pump 2, Copper transporting ATPase 2, PWD, Toxic milk, tx, WC1, WD, Wilson disease associated protein, Wilson disease-associated protein, WND, WND/140 kDa,
Application Dilution: WB: 1:500~1:2000, IF: 1:50~1:200
Specificity: ATP7B polyclonal antibody detects endogenous levels of ATP7B protein.
Immunogen:
Recombinant full length Human ATP7B.
MW: ~157 kDa
Swis Prot.: P35670
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein functions as a monomer, exporting copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease (WD).
Alternative Name:
ATP7B, ATP7B_HUMAN, ATPase, Cu(2+) transporting, beta polypeptide, ATPase, Cu++ transporting, beta polypeptide, Copper pump 2, Copper transporting ATPase 2, PWD, Toxic milk, tx, WC1, WD, Wilson disease associated protein, Wilson disease-associated protein, WND, WND/140 kDa,
Application Dilution: WB: 1:500~1:2000, IF: 1:50~1:200
Specificity: ATP7B polyclonal antibody detects endogenous levels of ATP7B protein.
Immunogen:
Recombinant full length Human ATP7B.
MW: ~157 kDa
Swis Prot.: P35670
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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