ATRIP polyclonal, anti-human, mouse
€388.00
In stock
SKU
BS8739
Background:
The product of the ATRIP gene is an essential component of the DNA damage checkpoint, and binds to single stranded DNA coated with replication protein A that accumulates at sites of DNA damage. The encoded protein interacts with the ataxia telangiectasia and Rad3 related protein, a checkpoint kinase, resulting in accumulation of the kinase at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene.
Alternative Name:
ATR-interacting protein, ATM and Rad3-related-interacting protein, ATRIP, AGS1
Application Dilution: WB: 1:500 - 1:2000, IP: 1:50 - 1:200
Specificity: ATRIP polyclonal antibody detects endogenous levels of ATRIP protein.
Immunogen:
Recombinant full length Human ATRIP.
MW: ~ 86kDa
Swis Prot.: Q8WXE1
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The product of the ATRIP gene is an essential component of the DNA damage checkpoint, and binds to single stranded DNA coated with replication protein A that accumulates at sites of DNA damage. The encoded protein interacts with the ataxia telangiectasia and Rad3 related protein, a checkpoint kinase, resulting in accumulation of the kinase at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene.
Alternative Name:
ATR-interacting protein, ATM and Rad3-related-interacting protein, ATRIP, AGS1
Application Dilution: WB: 1:500 - 1:2000, IP: 1:50 - 1:200
Specificity: ATRIP polyclonal antibody detects endogenous levels of ATRIP protein.
Immunogen:
Recombinant full length Human ATRIP.
MW: ~ 86kDa
Swis Prot.: Q8WXE1
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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