Aurora-B (ARK/STK12) Antibody (N-term) Blocking peptide
€293.00
In stock
SKU
AC-BP7001a
Background:
Chromosomal segregation during mitosis as well as meiosis is regulated by kinases and phosphatases. The Aurora kinases associate with microtubules during chromosome movement and segregation. Aurora kinase B localizes to microtubules near kinetochores, specifically to the specialized microtubules called K-fibers, and Aurora kinase A localizes to centrosomes.
Other Names: Aurora kinase B, Aurora 1, Aurora- and IPL1-like midbody-associated protein 1, AIM-1, Aurora/IPL1-related kinase 2, ARK-2, Aurora-related kinase 2, STK-1, Serine/threonine-protein kinase 12, Serine/threonine-protein kinase 5, Serine/threonine-protein kinase aurora-B, AURKB, AIK2, AIM1, AIRK2, ARK2, STK1, STK12, STK5
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7001a was selected from the N-term region of human Aurora-B . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Type: Synthetic peptide
Primary Accession: Q96GD4
Gene ID: 9212
Gene Name: AURKB
Format: The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
Bio References:
Kimura, M., et al., Biochem. Biophys. Res. Commun. 316(3):930-936 (2004).Yasui, Y., et al., J. Biol. Chem. 279(13):12997-13003 (2004).Lampson, M.A., et al., Nat. Cell Biol. 6(3):232-237 (2004).Wheatley, S.P., et al., J. Biol. Chem. 279(7):5655-5660 (2004).Honda, R., et al., Mol. Biol. Cell 14(8):3325-3341 (2003).
Chromosomal segregation during mitosis as well as meiosis is regulated by kinases and phosphatases. The Aurora kinases associate with microtubules during chromosome movement and segregation. Aurora kinase B localizes to microtubules near kinetochores, specifically to the specialized microtubules called K-fibers, and Aurora kinase A localizes to centrosomes.
Other Names: Aurora kinase B, Aurora 1, Aurora- and IPL1-like midbody-associated protein 1, AIM-1, Aurora/IPL1-related kinase 2, ARK-2, Aurora-related kinase 2, STK-1, Serine/threonine-protein kinase 12, Serine/threonine-protein kinase 5, Serine/threonine-protein kinase aurora-B, AURKB, AIK2, AIM1, AIRK2, ARK2, STK1, STK12, STK5
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7001a was selected from the N-term region of human Aurora-B . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Type: Synthetic peptide
Primary Accession: Q96GD4
Gene ID: 9212
Gene Name: AURKB
Format: The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
Bio References:
Kimura, M., et al., Biochem. Biophys. Res. Commun. 316(3):930-936 (2004).Yasui, Y., et al., J. Biol. Chem. 279(13):12997-13003 (2004).Lampson, M.A., et al., Nat. Cell Biol. 6(3):232-237 (2004).Wheatley, S.P., et al., J. Biol. Chem. 279(7):5655-5660 (2004).Honda, R., et al., Mol. Biol. Cell 14(8):3325-3341 (2003).
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