AXL Antibody (N-term) Blocking Peptide
€293.00
In stock
SKU
AC-BP7602a
Background:
AXL, a member of the AXL/UFO subfamily of Tyr protein kinases, may function as a signal transducer between specific cell types of mesodermal origin. This Type I membrane protein has transforming potential in patients with chronic myeloproliferative disorder or chronic myelocytic leukemia. The protein contains 2 putative fibronectin type III domains and 2 putative immunoglobulin-like C2-type domains.
Other Names: Tyrosine-protein kinase receptor UFO, AXL oncogene, AXL, UFO
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7602a was selected from the N-term region of human AXL . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Type: Synthetic peptide
Primary Accession: P30530
Gene ID: 558
Gene Name: AXL
Format: The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
Bio References:
Lee, S.T., et al., Oncogene 8(12):3403-3410 (1993).Janssen, J.W., et al., Oncogene 6(11):2113-2120 (1991).O'Bryan, J.P., et al., Mol. Cell. Biol. 11(10):5016-5031 (1991).Partanen, J., et al., Proc. Natl. Acad. Sci. U.S.A. 87(22):8913-8917 (1990).
AXL, a member of the AXL/UFO subfamily of Tyr protein kinases, may function as a signal transducer between specific cell types of mesodermal origin. This Type I membrane protein has transforming potential in patients with chronic myeloproliferative disorder or chronic myelocytic leukemia. The protein contains 2 putative fibronectin type III domains and 2 putative immunoglobulin-like C2-type domains.
Other Names: Tyrosine-protein kinase receptor UFO, AXL oncogene, AXL, UFO
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7602a was selected from the N-term region of human AXL . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Type: Synthetic peptide
Primary Accession: P30530
Gene ID: 558
Gene Name: AXL
Format: The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
Bio References:
Lee, S.T., et al., Oncogene 8(12):3403-3410 (1993).Janssen, J.W., et al., Oncogene 6(11):2113-2120 (1991).O'Bryan, J.P., et al., Mol. Cell. Biol. 11(10):5016-5031 (1991).Partanen, J., et al., Proc. Natl. Acad. Sci. U.S.A. 87(22):8913-8917 (1990).
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