B-Myb (phospho-S577) polyclonal, anti-human, mouse, rat
€328.00
In stock
SKU
BS4658
Background:
c-Myb is the cellular homolog of the leukemogenic avian retroviral protein v-Myc. c-Myb is expressed predominantly in immature and rapidly dividing hematopoietic cells, and cellular levels of c-Myb substantially decreases as cells reach terminal differentiation. B-Myb is expressed in a wide variety of proliferating cells, with levels accumulating during the G1 to S phase transition. A-Myb is expressed at specific times in reproductive tissues, some neural cells, and a subset of normal and neoplastic B lymphocytes.
Alternative Name:
Myb-related protein B, B Myb, Myb-like protein 2, MYBL2, BMYB
Application Dilution: WB: 1:500~1:1000
Specificity: p-B-Myb (S577) polyclonal antibody detects endogenous levels of B-Myb protein only when phosphorylated at Ser577.
Immunogen:
Synthetic phosphopeptide derived from human B-Myb around the phosphorylation site of Serine 577.
MW: ~ 80, 100 kDa
Swis Prot.: P10244
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
c-Myb is the cellular homolog of the leukemogenic avian retroviral protein v-Myc. c-Myb is expressed predominantly in immature and rapidly dividing hematopoietic cells, and cellular levels of c-Myb substantially decreases as cells reach terminal differentiation. B-Myb is expressed in a wide variety of proliferating cells, with levels accumulating during the G1 to S phase transition. A-Myb is expressed at specific times in reproductive tissues, some neural cells, and a subset of normal and neoplastic B lymphocytes.
Alternative Name:
Myb-related protein B, B Myb, Myb-like protein 2, MYBL2, BMYB
Application Dilution: WB: 1:500~1:1000
Specificity: p-B-Myb (S577) polyclonal antibody detects endogenous levels of B-Myb protein only when phosphorylated at Ser577.
Immunogen:
Synthetic phosphopeptide derived from human B-Myb around the phosphorylation site of Serine 577.
MW: ~ 80, 100 kDa
Swis Prot.: P10244
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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