Bacitracin::BSA Conjugate

Bacitracin::BSA Conjugate

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SKU
BW-40210023
Catalog Number: BW-40210023
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Product Description
Bacitracin is a mixture of related cyclic peptides. These peptides disrupt Gram-positive bacteria by interfering with cell wall and peptidoglycan synthesis. Unlike other oral administrative drugs, bacitracin is primarily used as a topical preparation as it can cause kidney damage. Bacitracin interferes with the dephosphorylation of bactoprenol, a membrane carrier molecule that transports the building blocks of the peptidoglycan bacterial cell wall outside of the inner membrane.

SA (bovine serum albumin) is conjugated to bacitracin (1:45). One or more of the three amine groups in bacitracin are directly linked to carboxyl group(s) in BSA. Bacitracin has a molecular weight of 1422.7 Da and BSA has a molecular weight of 66.4 kDa. The resultant conjugation solution is then buffer-exchanged with 20 mM PBS at a pH of 7.4.

Conjugated BSA-bacitracin is used to recognize bacitracin-specific antibodies by ELISA and lateral flow based immunoassay. Product can be stored below -20°C for up to 1 year.

Hazmat Shipping : Non-hazardous
Shelf life : 1 year
Storage : -20°C
Brand Name : bioPLUS
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