BAD polyclonal, anti-human, mouse, rat

Protein Family: Chaperones and Folding Catalysts

Pathway and Disease: Signal Transduction, Cell Growth and Death, Cell Communication, Endocrine System, Nervous and Sensory Systems, Cancers, Neurodegenerative Disorders, Infectious Diseases

Description:
Bcl2 antagonist of cell death (BAD) promotes cell death. BAD successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. BAD can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2. BAD acts as a link between growth factor receptor signaling and the apoptotic pathways.

Alternate Names: Bcl2 antagonist of cell death, BAD, Bcl-2-binding component 6, Bcl-2-like protein 8, Bcl2-L-8, Bcl-XL/Bcl-2-associated death promoter, BBC6, BCL2L8

Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500; IP: 1:100-1:500

Accession No.: Q92934

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human BAD.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.