BAI2 Antibody (C-term) Blocking Peptide
€293.00
In stock
SKU
AC-BP8171a
Background:
Angiogenesis is controlled by a local balance between stimulators and inhibitors of new vessel growth and is suppressed under normal physiologic conditions. Angiogenesis has been shown to be essential for growth and metastasis of solid tumors. In order to obtain blood supply for their growth, tumor cells are potently angiogenic and attract new vessels as results of increased secretion of inducers and decreased production of endogenous negative regulators. BAI1, a p53-target gene, encodes brain-specific angiogenesis inhibitor, a seven-span transmembrane protein and is thought to be a member of the secretin receptor family. Brain-specific angiogenesis proteins BAI2 and BAI3 are similar to BAI1 in structure, have similar tissue specificities and may also play a role in angiogenesis.
Other Names: Brain-specific angiogenesis inhibitor 2, BAI2
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP8171a was selected from the C-term region of human BAI2 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Type: Synthetic peptide
Primary Accession: O60241
Other Accession: NP_001694
Gene ID: 576
Gene Name: ADGRB2 (HGNC:944)
Format: The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
Bio References:
Kee, H.J., et al., J. Cereb. Blood Flow Metab. 22(9):1054-1067 (2002).Shiratsuchi, T., et al., Cytogenet. Cell Genet. 79 (1-2), 103-108 (1997).
Angiogenesis is controlled by a local balance between stimulators and inhibitors of new vessel growth and is suppressed under normal physiologic conditions. Angiogenesis has been shown to be essential for growth and metastasis of solid tumors. In order to obtain blood supply for their growth, tumor cells are potently angiogenic and attract new vessels as results of increased secretion of inducers and decreased production of endogenous negative regulators. BAI1, a p53-target gene, encodes brain-specific angiogenesis inhibitor, a seven-span transmembrane protein and is thought to be a member of the secretin receptor family. Brain-specific angiogenesis proteins BAI2 and BAI3 are similar to BAI1 in structure, have similar tissue specificities and may also play a role in angiogenesis.
Other Names: Brain-specific angiogenesis inhibitor 2, BAI2
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP8171a was selected from the C-term region of human BAI2 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Type: Synthetic peptide
Primary Accession: O60241
Other Accession: NP_001694
Gene ID: 576
Gene Name: ADGRB2 (HGNC:944)
Format: The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
Bio References:
Kee, H.J., et al., J. Cereb. Blood Flow Metab. 22(9):1054-1067 (2002).Shiratsuchi, T., et al., Cytogenet. Cell Genet. 79 (1-2), 103-108 (1997).
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