BAIAP2 Antibody (C-term) Blocking Peptide
€293.00
In stock
SKU
AC-BP8174a
Background:
BAIAP2, a target of p53, has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This interaction at the cytoplasmic membrane is crucial to the function of this protein, which may be involved in neuronal growth-cone guidance. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis.
Other Names: Brain-specific angiogenesis inhibitor 1-associated protein 2, BAI-associated protein 2, BAI1-associated protein 2, Protein BAP2, Fas ligand-associated factor 3, FLAF3, Insulin receptor substrate p53/p58, IRS-58, IRSp53/58, Insulin receptor substrate protein of 53 kDa, IRSp53, Insulin receptor substrate p53, BAIAP2
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP8174a was selected from the C-term region of human BAIAP2 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Type: Synthetic peptide
Primary Accession: Q9UQB8
Other Accession: NP_006331
Gene ID: 10458
Gene Name: BAIAP2
Format: The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
Bio References:
Fujiwara, T., et al., Biochem. Biophys. Res. Commun. 271(3):626-629 (2000).Abbott, M.A., et al., J. Neurosci. 19(17):7300-7308 (1999).Okamura-Oho, Y., et al., Hum. Mol. Genet. 8(6):947-957 (1999).Oda, K., et al., Cytogenet. Cell Genet. 84 (1-2), 75-82 (1999).
BAIAP2, a target of p53, has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This interaction at the cytoplasmic membrane is crucial to the function of this protein, which may be involved in neuronal growth-cone guidance. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis.
Other Names: Brain-specific angiogenesis inhibitor 1-associated protein 2, BAI-associated protein 2, BAI1-associated protein 2, Protein BAP2, Fas ligand-associated factor 3, FLAF3, Insulin receptor substrate p53/p58, IRS-58, IRSp53/58, Insulin receptor substrate protein of 53 kDa, IRSp53, Insulin receptor substrate p53, BAIAP2
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP8174a was selected from the C-term region of human BAIAP2 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Type: Synthetic peptide
Primary Accession: Q9UQB8
Other Accession: NP_006331
Gene ID: 10458
Gene Name: BAIAP2
Format: The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
Bio References:
Fujiwara, T., et al., Biochem. Biophys. Res. Commun. 271(3):626-629 (2000).Abbott, M.A., et al., J. Neurosci. 19(17):7300-7308 (1999).Okamura-Oho, Y., et al., Hum. Mol. Genet. 8(6):947-957 (1999).Oda, K., et al., Cytogenet. Cell Genet. 84 (1-2), 75-82 (1999).
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