BCAS3 Antibody (N-term) Blocking Peptide
€293.00
In stock
SKU
AC-BP2738a
Background:
Breast cancer amplified sequence 3 (BCAS3) was identified as a gene overexpressed and amplified in breast cancer cell lines. BCAS3 expression has been shown to be regulated by estrogen receptor alpha (ER alpha) and its coregulator PELP1 (proline-, glutamic acid-, and leucine-rich protein 1). BCAS3 has also been demonstrated to act as a coactivator of ER alpha activity in breast cancer cells and associate with the histone acetyltransferase complex protein P/CAF (p300/CBP-associated factor).
Other Names: Breast carcinoma-amplified sequence 3 {ECO:0000312|HGNC:HGNC:14347, ECO:0000312|MIM:607470}, GAOB1, BCAS3 {ECO:0000312|HGNC:HGNC:14347, ECO:0000312|MIM:607470}
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP2738a was selected from the N-term region of human BCAS3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Type: Synthetic peptide
Primary Accession: Q9H6U6
Gene ID: 54828
Gene Name: BCAS3 {ECO:0000312|HGNC:HGNC:14347, ECO:0000312|MIM:607470}
Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Bio References:
Baerlund M.,Genes Chromosomes Cancer 35:311-317(2002).Strausberg,R.L.,Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
Breast cancer amplified sequence 3 (BCAS3) was identified as a gene overexpressed and amplified in breast cancer cell lines. BCAS3 expression has been shown to be regulated by estrogen receptor alpha (ER alpha) and its coregulator PELP1 (proline-, glutamic acid-, and leucine-rich protein 1). BCAS3 has also been demonstrated to act as a coactivator of ER alpha activity in breast cancer cells and associate with the histone acetyltransferase complex protein P/CAF (p300/CBP-associated factor).
Other Names: Breast carcinoma-amplified sequence 3 {ECO:0000312|HGNC:HGNC:14347, ECO:0000312|MIM:607470}, GAOB1, BCAS3 {ECO:0000312|HGNC:HGNC:14347, ECO:0000312|MIM:607470}
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP2738a was selected from the N-term region of human BCAS3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Type: Synthetic peptide
Primary Accession: Q9H6U6
Gene ID: 54828
Gene Name: BCAS3 {ECO:0000312|HGNC:HGNC:14347, ECO:0000312|MIM:607470}
Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Bio References:
Baerlund M.,Genes Chromosomes Cancer 35:311-317(2002).Strausberg,R.L.,Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
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