BCDIN3D Blocking Peptide (C-Term)

BCDIN3D Blocking Peptide (C-Term)

€293.00
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SKU
AC-BP22145b
Catalog Number: AC-BP22145b
Size: 500 µg
Datasheet

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Background:
O-methyltransferase that specifically dimethylates the 5' monophosphate of pre-miRNAs, acting as a negative regulator of miRNA processing. The 5' monophosphate of pre-miRNAs is recognized by DICER1 and is required for pre-miRNAs processing: methylation at this position reduces the processing of pre-miRNAs by DICER1. Able to mediate methylation of pre-miR-145, as well as other pre- miRNAs.

Other Names: Pre-miRNA 5'-monophosphate methyltransferase, 2.1.1.-, BCDIN3 domain-containing protein, BCDIN3D

Target/Specificity:
The synthetic peptide sequence is selected from aa 263-276 of HUMAN BCDIN3D

Type: Synthetic peptide

Primary Accession: Q7Z5W3

Other Accession: Q5RFI3

Gene ID: 144233

Gene Name: BCDIN3D (HGNC:27050)

Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.

Bio References:
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Xhemalce B.,et al.Cell 151:278-288(2012).
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