BCHE Antibody (Center) Blocking Peptide

BCHE Antibody (Center) Blocking Peptide

€293.00
In stock
SKU
AC-BP7829c
Catalog Number: AC-BP7829c
Size: 500 µg
Datasheet

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Background:
Mutant proteins of BCHE are responsible for suxamethonium sensitivity. Homozygous persons sustain prolonged apnea after administration of the muscle relaxant suxamethonium in connection with surgical anesthesia. The activity of pseudocholinesterase in the serum is low and its substrate behavior is atypical. In the absence of the relaxant, the homozygote is at no known disadvantage.

Other Names: Cholinesterase, Acylcholine acylhydrolase, Butyrylcholine esterase, Choline esterase II, Pseudocholinesterase, BCHE, CHE1

Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7829c was selected from the Center region of human BCHE. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.

Type: Synthetic peptide

Primary Accession: P06276

Gene ID: 590

Gene Name: BCHE

Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.

Bio References:
Primo-Parmo S.L., Bartels C.F.Am. J. Hum. Genet. 58:52-64(1996)Primo-Parmo S.L., Lightstone H.Pharmacogenetics 7:27-34(1997) Yen T., Nightingale B.N.Clin. Chem. 49:1297-1308(2003)
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