BCL-2 (clone 8E12), anti-human, mouse
€394.00
In stock
SKU
253037
Catalog Nr.: 253037
Size: 0.1 ml
Isotype: Mouse IgG1
Applications: IF, IHC
Size: 0.1 ml
Isotype: Mouse IgG1
Applications: IF, IHC
Protein Family: Enzymes, Receptors and Channels
Pathway and Disease: Cancers, Cell Communication, Cell Growth and Death, Membrane Transport, Neurodegenerative Disorders
Description:
Bcl-2 blocks cell death following a variety of stimuli and confers a death-sparing effect to certain hematopoietic cell lines following growth factor withdrawal. Bcl-2 regulates cell death by controlling the mitochondrial membrane permeability. Bcl-2 functions in a feedback loop system with caspases by inhibiting caspase activity either by preventing the release of cytochrome c from the mitochondria or by binding to the apoptosis-activating factor (APAF-1).
Alternate Names: Apoptosis regulator Bcl-2, BCL2
Application Notes: IHC: 1:200-1:1000; IF: 1:200-1:1000
Accession No.: P10415
Antigen: Synthetic peptide corresponding to residues surrounding BCL-2, conjugated to KLH.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Pathway and Disease: Cancers, Cell Communication, Cell Growth and Death, Membrane Transport, Neurodegenerative Disorders
Description:
Bcl-2 blocks cell death following a variety of stimuli and confers a death-sparing effect to certain hematopoietic cell lines following growth factor withdrawal. Bcl-2 regulates cell death by controlling the mitochondrial membrane permeability. Bcl-2 functions in a feedback loop system with caspases by inhibiting caspase activity either by preventing the release of cytochrome c from the mitochondria or by binding to the apoptosis-activating factor (APAF-1).
Alternate Names: Apoptosis regulator Bcl-2, BCL2
Application Notes: IHC: 1:200-1:1000; IF: 1:200-1:1000
Accession No.: P10415
Antigen: Synthetic peptide corresponding to residues surrounding BCL-2, conjugated to KLH.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
| Is Featured? | No |
|---|
Write Your Own Review