Bcl-2 (phospho Ser70) Polyclonal Antibody

Background:
BCL2 encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants.

Alternative Names:
BCL2, Apoptosis regulator Bcl-2

Immunogen: The antiserum was produced against synthesized peptide derived from human BCL2 around the phosphorylation site of Ser70. AA range:36-85

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 26

GeneID: BCL2

Storage: -20°C/1 year

NOTE: For Research Use Only