Bcl-2 polyclonal, anti-human, mouse, rat
€378.00
In stock
SKU
250555
Catalog Nr.: 250555
Size: 0.1 mg
Isotype: Rabbit Ig
Applications: E, WB, IHC, IP
Size: 0.1 mg
Isotype: Rabbit Ig
Applications: E, WB, IHC, IP
Protein Family: Enzymes, Receptors and Channels
Pathway and Disease: Cancers, Cell Communication, Cell Growth and Death, Membrane Transport, Neurodegenerative Disorders
Description:
Bcl-2 blocks cell death following a variety of stimuli and confers a death-sparing effect to certain hematopoietic cell lines following growth factor withdrawal. Bcl-2 regulates cell death by controlling the mitochondrial membrane permeability. Bcl-2 functions in a feedback loop system with caspases by inhibiting caspase activity either by preventing the release of cytochrome c from the mitochondria or by binding to the apoptosis-activating factor (APAF-1).
Alternate Names: Apoptosis regulator Bcl-2, BCL2
Application Notes: E: 1:500-1:1,000; WB: 1:200-1:500; IHC: 1:200-1:500
Accession No.: P10415
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human Bcl-2.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Pathway and Disease: Cancers, Cell Communication, Cell Growth and Death, Membrane Transport, Neurodegenerative Disorders
Description:
Bcl-2 blocks cell death following a variety of stimuli and confers a death-sparing effect to certain hematopoietic cell lines following growth factor withdrawal. Bcl-2 regulates cell death by controlling the mitochondrial membrane permeability. Bcl-2 functions in a feedback loop system with caspases by inhibiting caspase activity either by preventing the release of cytochrome c from the mitochondria or by binding to the apoptosis-activating factor (APAF-1).
Alternate Names: Apoptosis regulator Bcl-2, BCL2
Application Notes: E: 1:500-1:1,000; WB: 1:200-1:500; IHC: 1:200-1:500
Accession No.: P10415
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human Bcl-2.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
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