BCL2L1 Antibody (N-term) Blocking Peptide
€293.00
In stock
SKU
AC-BP7958a
Background:
BCL2L1 belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis.
Other Names: Bcl-2-like protein 1, Bcl2-L-1, Apoptosis regulator Bcl-X, BCL2L1, BCL2L, BCLX
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7958a was selected from the N-term region of human BCL2L1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Type: Synthetic peptide
Primary Accession: Q07817
Gene ID: 598
Gene Name: BCL2L1
Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Bio References:
Boise L.H., Gonzalez-Garcia M.Cell 74:597-608(1993)Lo S.-C., Hannink M.J. Biol. Chem. 281:37893-37903(2006) Petros A.M., Nettesheim D.G.Protein Sci. 9:2528-2534(2000)
BCL2L1 belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis.
Other Names: Bcl-2-like protein 1, Bcl2-L-1, Apoptosis regulator Bcl-X, BCL2L1, BCL2L, BCLX
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7958a was selected from the N-term region of human BCL2L1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Type: Synthetic peptide
Primary Accession: Q07817
Gene ID: 598
Gene Name: BCL2L1
Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Bio References:
Boise L.H., Gonzalez-Garcia M.Cell 74:597-608(1993)Lo S.-C., Hannink M.J. Biol. Chem. 281:37893-37903(2006) Petros A.M., Nettesheim D.G.Protein Sci. 9:2528-2534(2000)
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