BCOR Antibody (Center S1122) Blocking Peptide
€293.00
In stock
SKU
AC-BP7359c
Background:
BCOR was identified as an interacting corepressor of BCL6, a POZ/zinc finger transcription repressor that is required for germinal center formation and may influence apoptosis. This protein selectively interacts with the POZ domain of BCL6, but not with eight other POZ proteins. Specific class I and II histone deacetylases (HDACs) have been shown to interact with this protein, which suggests a possible link between the two classes of HDACs.
Other Names: BCL-6 corepressor, BCoR, BCOR, KIAA1575
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7359c was selected from the Center region of human BCOR. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Type: Synthetic peptide
Primary Accession: Q6W2J9
Gene ID: 54880
Gene Name: BCOR
Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Bio References:
Ghetu,A.F., Mol. Cell 29 (3), 384-391 (2008)Hilton,E.N., Hum. Mol. Genet. 16 (14), 1773-1782 (2007)
BCOR was identified as an interacting corepressor of BCL6, a POZ/zinc finger transcription repressor that is required for germinal center formation and may influence apoptosis. This protein selectively interacts with the POZ domain of BCL6, but not with eight other POZ proteins. Specific class I and II histone deacetylases (HDACs) have been shown to interact with this protein, which suggests a possible link between the two classes of HDACs.
Other Names: BCL-6 corepressor, BCoR, BCOR, KIAA1575
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7359c was selected from the Center region of human BCOR. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Type: Synthetic peptide
Primary Accession: Q6W2J9
Gene ID: 54880
Gene Name: BCOR
Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Bio References:
Ghetu,A.F., Mol. Cell 29 (3), 384-391 (2008)Hilton,E.N., Hum. Mol. Genet. 16 (14), 1773-1782 (2007)
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