BDK_1 Antibody (Center) Blocking peptide
€293.00
In stock
SKU
AC-BP8735c
Background:
Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. BDKRB1 is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses.
Other Names: B1 bradykinin receptor, B1R, BK-1 receptor, BDKRB1, BRADYB1
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP8735c was selected from the Center region of human BDKRB1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Type: Synthetic peptide
Primary Accession: P46663
Gene ID: 623
Gene Name: BDKRB1
Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Bio References:
Bachvarov,D.R., et.al., Genomics 33 (3), 374-381 (1996)
Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. BDKRB1 is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses.
Other Names: B1 bradykinin receptor, B1R, BK-1 receptor, BDKRB1, BRADYB1
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP8735c was selected from the Center region of human BDKRB1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Type: Synthetic peptide
Primary Accession: P46663
Gene ID: 623
Gene Name: BDKRB1
Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Bio References:
Bachvarov,D.R., et.al., Genomics 33 (3), 374-381 (1996)
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