Beta-Actin polyclonal, anti-human, mouse, rat, sheep, pig, bovine
€362.00
In stock
SKU
250920
Catalog Nr.: 250920
Size: 0.1 mg
Isotype: Rabbit Ig
Applications: E, WB, IHC
Size: 0.1 mg
Isotype: Rabbit Ig
Applications: E, WB, IHC
Protein Family: Cytoskeleton Proteins
Pathway and Disease: Cell Communication, Cell Motility, Immune System, Infectious Diseases
Description:
Actins are highly conserved proteins involved in cell motility that are ubiquitously expressed in eukaryotic cells. There are 3 main actin isoforms in vertebrates: alpha, beta and gamma. The alpha actins are found in muscles and are a major constituent of the contractile apparatus. The beta and gamma actins coexist in most cell types as components of the cytoskeleton and mediators of internal cell motility. Defects in beta-actin are a cause of juvenile-onset dystonia, a movement disorder with a neurological basis. This antibody is well suited as positive control for many cell lines and tissues.
Alternate Names: Actin, cytoplasmic 1, Beta-actin, ACTB
Application Notes: E: 1:500-1:1,000; WB: 1:200-1:500; IHC: 1:200-1:500
Accession No.: P60709
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human beta-actin.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 25% glycerol, 1 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Product Citations:
[1] Zhu J. et al. 2015. Mol Med Rep. doi:10.3892/mmr.2015.3284. PMID# 25634369.
[2] Meng Q. et al. 2014. Biomedical and Life Sciences. Tumor Biol. 35(12):12265-74. PMID# 25168370.
[3] Hua L et al. 2013.Tumor Biology.PMID# 24114014.
[4] Sun Q et al. PMID# 23857284.
[5] Li Y et al. 2013. PMID# 23801152.
[6] Jianwei Z et al. 2013.PMID# 23740615.
[7] Yingjie L et al. 2013. PMID# 23681800
[8] Yu, G et al. 2013. PMID# 22983920.
[8] Zhong L et al. 2013. PMID# 23055197.
[9] Li Y et al. 2012. PMID# 22528939.
[10] Chen E et al. PMID# 22488244.
[11] Wei S et al. 2012. PMID# 22392501.
[12] Xu Y et al. 2011. PMID# 22143536.
Pathway and Disease: Cell Communication, Cell Motility, Immune System, Infectious Diseases
Description:
Actins are highly conserved proteins involved in cell motility that are ubiquitously expressed in eukaryotic cells. There are 3 main actin isoforms in vertebrates: alpha, beta and gamma. The alpha actins are found in muscles and are a major constituent of the contractile apparatus. The beta and gamma actins coexist in most cell types as components of the cytoskeleton and mediators of internal cell motility. Defects in beta-actin are a cause of juvenile-onset dystonia, a movement disorder with a neurological basis. This antibody is well suited as positive control for many cell lines and tissues.
Alternate Names: Actin, cytoplasmic 1, Beta-actin, ACTB
Application Notes: E: 1:500-1:1,000; WB: 1:200-1:500; IHC: 1:200-1:500
Accession No.: P60709
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human beta-actin.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 25% glycerol, 1 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Product Citations:
[1] Zhu J. et al. 2015. Mol Med Rep. doi:10.3892/mmr.2015.3284. PMID# 25634369.
[2] Meng Q. et al. 2014. Biomedical and Life Sciences. Tumor Biol. 35(12):12265-74. PMID# 25168370.
[3] Hua L et al. 2013.Tumor Biology.PMID# 24114014.
[4] Sun Q et al. PMID# 23857284.
[5] Li Y et al. 2013. PMID# 23801152.
[6] Jianwei Z et al. 2013.PMID# 23740615.
[7] Yingjie L et al. 2013. PMID# 23681800
[8] Yu, G et al. 2013. PMID# 22983920.
[8] Zhong L et al. 2013. PMID# 23055197.
[9] Li Y et al. 2012. PMID# 22528939.
[10] Chen E et al. PMID# 22488244.
[11] Wei S et al. 2012. PMID# 22392501.
[12] Xu Y et al. 2011. PMID# 22143536.
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