beta Tubulin Monoclonal Antibody

Background:
There are five tubulins in human cells: alpha, beta, gamma, delta, and epsilon. Tubulins are conserved across species. They form heterodimers, which multimerize to form a microtubule filament. An alpha and beta tubulin heterodimer is the basic structural unit of microtubules. The heterodimer does not come apart, once formed. The alpha and beta tubulins, which are each about 55 kDa MW, are homologous but not identical. Alpha, beta, and gamma tubulins have all been used as loading controls. Tubulin expression may vary according to resistance to antimicrobial and antimitotic drugs.

Research Area: Cancer, Neuroscience, Signal Transduction, Tags and Cell Markers

Synonyms:
beta 3 tubulin, beta-4, CDCBM, CDCBM1, CFEOM3, CFEOM3A, FEOM3, M(beta)3, M(beta)6, MC1R, Neuron specific beta III Tubulin, Neuron-specific class III beta-tubulin, QccE-11995, QccE-15186, TBB3, Tubb 3, TUBB3, TUBB4, Tubulin beta 3, Tubulin beta 3 chain, Tubulin beta 4, Tubulin beta III, Tubulin beta-3 chain, Tubulin beta-4 chain, Tubulin beta-III

Immunogen: Synthetic Peptide

Swissprot: Q13509

Calculated MW: 50 kDa
Observed MW: 55 kDa

Purification Method: Protein A purification

Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.

Concentration: 1 mg/mL
Dilution: WB 1:5000-1:10000, IHC 1:100-1:300, IF 1:100-1:300

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Citation(s):
https://www.sciencedirect.com/science/article/pii/S0960076018307465
https://www.mdpi.com/1422-0067/20/5/1049/htm
https://www.sciencedirect.com/science/article/pii/S1043661818310387
https://pubmed.ncbi.nlm.nih.gov/31943336/
https://pubmed.ncbi.nlm.nih.gov/32557748/
https://pubmed.ncbi.nlm.nih.gov/32598510/
https://pubmed.ncbi.nlm.nih.gov/32692841/