Bmi1 (clone ), anti-human, mouse, rat
€428.00
In stock
SKU
MB9014
Background:
Bmi-1 has been identified as a potent oncogene as it contributes to the transcriptional activation of genes implicated in early lymphoid development. Proviral activation of Bmi-1 expression corresponds to enhanced gene-specific activation of other proto-oncogenes, including c-Myc and Pim, subsequently resulting in the progression of lymphomagenesis.
Alternative Name:
Polycomb complex protein BMI-1, Polycomb group RING finger protein 4, RING finger protein 51, BMI1, PCGF4, RNF51
Application Dilution: WB: 1:1000, IHC/ICC: 1:100-1:200, FC: 1:100-1:200
Specificity: This antibody detects endogenous levels of Bmi1 and does not cross-react with related proteins.
Immunogen:
This antibody is produced by immunizing mice with a recombinant protein corresponding to a region of Bmi1.
MW: ~ 37 kDa
Swis Prot.: P35226
Purification & Purity:
Protein A affinity purified
Format:
Mouse IgG2a. 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Bmi-1 has been identified as a potent oncogene as it contributes to the transcriptional activation of genes implicated in early lymphoid development. Proviral activation of Bmi-1 expression corresponds to enhanced gene-specific activation of other proto-oncogenes, including c-Myc and Pim, subsequently resulting in the progression of lymphomagenesis.
Alternative Name:
Polycomb complex protein BMI-1, Polycomb group RING finger protein 4, RING finger protein 51, BMI1, PCGF4, RNF51
Application Dilution: WB: 1:1000, IHC/ICC: 1:100-1:200, FC: 1:100-1:200
Specificity: This antibody detects endogenous levels of Bmi1 and does not cross-react with related proteins.
Immunogen:
This antibody is produced by immunizing mice with a recombinant protein corresponding to a region of Bmi1.
MW: ~ 37 kDa
Swis Prot.: P35226
Purification & Purity:
Protein A affinity purified
Format:
Mouse IgG2a. 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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