BRCA2 polyclonal, anti-human, mouse, rat

Protein Family: Transcription Factors, Ubiquitins

Pathway and Disease: Cancers, Cell Growth and Death, Folding, Sorting and Degradation, Replication and Repair, Transcription

Description:
Breast cancer type 2 susceptibility protein (BRCA2) is involved in double-strand break repair and homologous recombination as well as in S phase checkpoint activation. Defects in BRCA2 are a cause of genetic susceptibility to breast and ovarian cancers as well as the cause of Fanconi anemia complementation group D type 1 (FANCD1).

Alternate Names: BRCA2, Breast cancer type 2 susceptibility protein, Fanconi anemia group D1 protein, FACD, FANCD1

Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500

Accession No.: P51587

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human BRCA2.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.