C-Peptide polyclonal, anti-human

Protein Family: Hormones

Pathway and Disease: Cancers, Cell Motility, Endocrine System, Folding, Sorting and Degradation, Metabolic Disorders, Neurodegenerative Disorders, Signal Transduction

Description:
Insulin decreases blood glucose concentration and increases cell permeability to monosaccharides, amino acids and fatty acids. Insulin accelerates glycolysis, the pentose phosphate cycle and glycogen synthesis in liver. Defects in insulin are the cause of familial hyperproinsulinemia. Insulin is available under the names Humulin or Humalog (Eli Lilly) and Novolin (Novo Nordisk) for the treatment of diabetes. After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into two chains: peptide A and peptide B, covalently linked by two disulfide bonds.

Alternate Names: C-peptide, insulin, INS, proinsulin

Application Notes: E: 1:500-1:1,000; WB: 1:200-1:500; IHC: 1:200-1:500

Accession No.: P01308

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human C-Peptide.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.