C1 Inhibitor (clone KT28), anti-human
€354.00
In stock
SKU
250122
Catalog Nr.: 250122
Size: 0.1 mg
Isotype: mouse IgG1
Applications: E
Size: 0.1 mg
Isotype: mouse IgG1
Applications: E
Protein Family: Proteoglycans
Pathway and Disease: Immune System
Description:
The complement C1 inhibitor controls the activation of the C1 complex by forming a proteolytically inactive stoichiometric complex with the C1r or C1s proteases. This process regulates important physiological pathways including complement activation, blood coagulation, fibrinolysis and the generation of kinins. Deficiencies in C1 inhibitor cause hereditary angiodema (HAE/HANE), a disorder characterized by episodic local subcutaneous edema and submucosal edema involving the upper respiratory and gastrointestinal tracts. This antibody recognizes human complement C1 inhibitor by ELISA.
Alternate Names: Plasma protease C1 inhibitor, C1 Inh, C1Inh, C1 esterase inhibitor, C1-inhibiting factor, SERPING1, C1IN, C1NH
Application Notes: E: 5 mg/ml
Accession No.: P05155, NP_000053
Antigen: Purified human complement C1 inhibitor protein
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Pathway and Disease: Immune System
Description:
The complement C1 inhibitor controls the activation of the C1 complex by forming a proteolytically inactive stoichiometric complex with the C1r or C1s proteases. This process regulates important physiological pathways including complement activation, blood coagulation, fibrinolysis and the generation of kinins. Deficiencies in C1 inhibitor cause hereditary angiodema (HAE/HANE), a disorder characterized by episodic local subcutaneous edema and submucosal edema involving the upper respiratory and gastrointestinal tracts. This antibody recognizes human complement C1 inhibitor by ELISA.
Alternate Names: Plasma protease C1 inhibitor, C1 Inh, C1Inh, C1 esterase inhibitor, C1-inhibiting factor, SERPING1, C1IN, C1NH
Application Notes: E: 5 mg/ml
Accession No.: P05155, NP_000053
Antigen: Purified human complement C1 inhibitor protein
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
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