C11orf95-RELA Fusion FISH Probe

Fusions involving C11orf95 and RELA can lead to the up-regulation of NFKB gene and drive tumor genesis. Patients harboring this fusion often have a poorer prognosis than other variations of the disease. Up to 70% of supratentorially arisen edendymomas involve recurrent RELA fusions. Our tri-color RELA-C11orf95 fusion probe can help to detect these significant aberrations and help guide treatment.