C3 Complement (clone 2D8), anti-human
€407.00
In stock
SKU
250289
Catalog Nr.: 250289
Size: 0.1 mg
Isotype: Mouse IgG1/k
Applications: E, WB
Size: 0.1 mg
Isotype: Mouse IgG1/k
Applications: E, WB
Protein Family: Enzymes, CAM ligands, Cellular Adhesion Molecules
Pathway and Disease: Immune System, Cell Communication
Description:
C3 is a key component of the complement system since classical and alternative activation pathways merge at the C3 activation step when C3 is split into C3a and C3b. The molecular mass of C3 is 185 kDa and it consists of two chains (110 kDa and 75 kDa) held together by disulfide bonds. This antibody is specific for human C3.
Alternate Names: C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1, Complement C3, C3a anaphylatoxin, Complement C3b alpha chain, Complement C3c alpha chain fragment 1, Complement C3dg fragment, C3d fragment, C3g fragment, C3f fragment, C3c alpha chain fragment 2
Application Notes: Product Cat. No. 250289 reacts strongly with C3. Strong reaction is seen in ELISA with C3 directly coated onto the microtiter well, and also when tested in sandwich ELISA in combination with a polyclonal antibody against C3. In Western blot, Product Cat. No. 250289 reacts with C3 in reduced as well as non-reduced forms. E: 1:16,000; WB: 1:1,000
Accession No.: P01024
Antigen: C3 isolated from human plasma
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography.
Storage:
Store at 4°C. Product is guaranteed 6 months from the date of shipment.
Product Citations:
Agrahari G et al. 2013. J Biol Chem. 2013. 288(38):27494-27504. PMID# 23928307. Complement-mediated Opsonization of Invasive Group A Streptococcus pyogenes Strain AP52 is Regulated by the Bacterial Two-component Cluster of Virulence Responder/Sensor (CovRS) System.
Pathway and Disease: Immune System, Cell Communication
Description:
C3 is a key component of the complement system since classical and alternative activation pathways merge at the C3 activation step when C3 is split into C3a and C3b. The molecular mass of C3 is 185 kDa and it consists of two chains (110 kDa and 75 kDa) held together by disulfide bonds. This antibody is specific for human C3.
Alternate Names: C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1, Complement C3, C3a anaphylatoxin, Complement C3b alpha chain, Complement C3c alpha chain fragment 1, Complement C3dg fragment, C3d fragment, C3g fragment, C3f fragment, C3c alpha chain fragment 2
Application Notes: Product Cat. No. 250289 reacts strongly with C3. Strong reaction is seen in ELISA with C3 directly coated onto the microtiter well, and also when tested in sandwich ELISA in combination with a polyclonal antibody against C3. In Western blot, Product Cat. No. 250289 reacts with C3 in reduced as well as non-reduced forms. E: 1:16,000; WB: 1:1,000
Accession No.: P01024
Antigen: C3 isolated from human plasma
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography.
Storage:
Store at 4°C. Product is guaranteed 6 months from the date of shipment.
Product Citations:
Agrahari G et al. 2013. J Biol Chem. 2013. 288(38):27494-27504. PMID# 23928307. Complement-mediated Opsonization of Invasive Group A Streptococcus pyogenes Strain AP52 is Regulated by the Bacterial Two-component Cluster of Virulence Responder/Sensor (CovRS) System.
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