C3 Complement (clone 7C10), anti-human

Protein Family: Enzymes, CAM ligands, Cellular Adhesion Molecules

Pathway and Disease: Immune System, Cell Communication

Description:
C3 is a key component of the complement system since classical and alternative activation pathways merge at the C3 activation step when C3 is split into C3a and C3b. The molecular mass of C3 is 185 kDa and it consists of two chains (110 kDa and 75 kDa) held together by disulfide bonds. This antibody is specific for human C3d, a fragment of the alpha chain.

Alternate Names: C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1, Complement C3, C3a anaphylatoxin, Complement C3b alpha chain, Complement C3c alpha chain fragment 1, Complement C3dg fragment, C3d fragment, C3g fragment, C3f fragment, C3c alpha chain fragment 2

Application Notes: Product Cat. No. 250285 reacts strongly with C3. Strong reaction is seen in ELISA with human C3 coated directly onto the microtiter well, or when used as detection antibody in sandwich ELISA in combination with a polyclonal C3 antibody. Product Cat. No. 250285 also reacts with C3b deposited on coated antibody molecules. In Western blotting, Product Cat. No. 250285 reacts with C3 in both reduced and unreduced forms. E: 1:16,000; WB: 1:1,000

Accession No.: P01024

Antigen: C3 isolated from human plasma

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography.

Storage:
Store at 4°C. Product is guaranteed 6 months from the date of shipment.