C3 Complement (clone KT17), anti-human
€354.00
In stock
SKU
250121
Catalog Nr.: 250121
Size: 0.1 mg
Isotype: Mouse IgG2b
Applications: E
Size: 0.1 mg
Isotype: Mouse IgG2b
Applications: E
Protein Family: Cell Adhesion Molecules, CAM Ligands, Enzymes
Pathway and Disease: Immune System
Description:
The complement component C3 plays a central role in the activation of the complement system. C3 activation by the C3 convertase is the central reaction in both classical and alternative complement pathways. Cleaved C3 produces C3a anaphylatoxin, a mediator of local inflammatory process, and C3b, which binds to cell surface carbohydrates and immune aggregates. Genetic variation in C3 is associated with susceptibility to age-related macular degeneration 9 (ARMD9). This antibody recognizes the human complement C3 in ELISA.
Alternate Names: C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1, Complement C3, C3a anaphylatoxin, Complement C3b alpha chain, Complement C3c alpha chain fragment 1, Complement C3dg fragment, C3d fragment, C3g fragment, C3f fragment, C3c alpha chain fragment 2
Application Notes: E: 5 ug/ml
Accession No.: P01024, NP_000055
Antigen: Purified human complement C3 protein
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Product Citations:
Lindblom R et al. 2014. J Immunol. 192(3): 1138-1153. PMID# 24353269.
Pathway and Disease: Immune System
Description:
The complement component C3 plays a central role in the activation of the complement system. C3 activation by the C3 convertase is the central reaction in both classical and alternative complement pathways. Cleaved C3 produces C3a anaphylatoxin, a mediator of local inflammatory process, and C3b, which binds to cell surface carbohydrates and immune aggregates. Genetic variation in C3 is associated with susceptibility to age-related macular degeneration 9 (ARMD9). This antibody recognizes the human complement C3 in ELISA.
Alternate Names: C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1, Complement C3, C3a anaphylatoxin, Complement C3b alpha chain, Complement C3c alpha chain fragment 1, Complement C3dg fragment, C3d fragment, C3g fragment, C3f fragment, C3c alpha chain fragment 2
Application Notes: E: 5 ug/ml
Accession No.: P01024, NP_000055
Antigen: Purified human complement C3 protein
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Product Citations:
Lindblom R et al. 2014. J Immunol. 192(3): 1138-1153. PMID# 24353269.
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