C3 Complement Rat (clone 12E2), anti-rat
€407.00
In stock
SKU
250346
Catalog Nr.: 250346
Size: 0.1 mg
Isotype: Mouse IgG1/k
Applications: E, IHC
Size: 0.1 mg
Isotype: Mouse IgG1/k
Applications: E, IHC
Protein Family: Enzymes, CAM ligands, Cellular Adhesion Molecules
Pathway and Disease: Immune System, Cell Communication
Description:
C3 is a key component of the complement system, because the lectin, classical and alternative activation pathways merge at the C3 activation step. This antibody is specific for rat C3. No cross-reaction is seen when tested with human C3.
Alternate Names: Complement C3, C3a anaphylatoxin, Complement C3b alpha chain, Complement C3c alpha chain fragment 1, Complement C3dg fragment, C3d fragment, C3g fragment, C3f fragment, C3c alpha chain fragment 2
Application Notes: Product Cat. No. 250346 reacts strongly with rat C3 when tested in sandwich ELISA in combination with a polyclonal antibody against rat C3. The antibody prolongs xenograft survival in rats transplanted with guinea-pig hearts. E: 1:4,000; IHC: 1:500
Accession No.: P01026
Antigen: C3 purified from rat serum
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography.
Storage:
Store at 4°C. Product is guaranteed 6 months from the date of shipment.
Product Citations:
[1] Pedros C et al. 2013. Genes and Immunity. doi:10.1038/gene.2013.21. PMID#23615071
[2] Nimer F et al. 2013. Elsevier. Brain, Behavior, and Immunity. 27:109-122. PMID# 23044177.
[3] Unadkat J et al. 2009. Transplantation Proceedings. 41(2):542-545. PMID# 19328922.
Pathway and Disease: Immune System, Cell Communication
Description:
C3 is a key component of the complement system, because the lectin, classical and alternative activation pathways merge at the C3 activation step. This antibody is specific for rat C3. No cross-reaction is seen when tested with human C3.
Alternate Names: Complement C3, C3a anaphylatoxin, Complement C3b alpha chain, Complement C3c alpha chain fragment 1, Complement C3dg fragment, C3d fragment, C3g fragment, C3f fragment, C3c alpha chain fragment 2
Application Notes: Product Cat. No. 250346 reacts strongly with rat C3 when tested in sandwich ELISA in combination with a polyclonal antibody against rat C3. The antibody prolongs xenograft survival in rats transplanted with guinea-pig hearts. E: 1:4,000; IHC: 1:500
Accession No.: P01026
Antigen: C3 purified from rat serum
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography.
Storage:
Store at 4°C. Product is guaranteed 6 months from the date of shipment.
Product Citations:
[1] Pedros C et al. 2013. Genes and Immunity. doi:10.1038/gene.2013.21. PMID#23615071
[2] Nimer F et al. 2013. Elsevier. Brain, Behavior, and Immunity. 27:109-122. PMID# 23044177.
[3] Unadkat J et al. 2009. Transplantation Proceedings. 41(2):542-545. PMID# 19328922.
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