C3a/C3a desArg Complement (clone K13/16), anti-human

C3a/C3a desArg Complement (clone K13/16), anti-human

€747.00
In stock
SKU
250277
Catalog Nr.: 250277
Size: 0.2 mg
Isotype: Mouse IgG1/k
Applications: E, WB
Protein Family: CAM ligands, Cell Adhesion Molecules, Receptors and Signaling Molecules

Pathway and Disease: Signaling Molecules and Interaction, Immune System

Description:
Complement C3a is an anaphylatoxin of 77 amino acid residues released by the action of the C3 convertases on the N-terminal of the alpha chain of C3. It is rapidly inactivated by serum carboxypeptidase N which removes the C-terminal arginine residue generating C3a (desArg). This antibody recognizes an epitope that is present on human C3, C3a and C3a (desArg) and does not react with C4a or C5a.

Alternate Names: C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1, Complement C3, C3a anaphylatoxin, Complement C3b alpha chain, Complement C3c alpha chain fragment 1, Complement C3dg fragment, C3d fragment, C3g fragment, C3f fragment, C3c alpha chain fragment 2

Application Notes: Product Cat. No. 250277 can be used as a capture antibody in sandwich ELISA with Product Cat. No. 250278 as detection antibody. Product Cat. No. 250277 can also be used to immunopurify C3a. Effectively inhibits the biological activitiy of C3a in a guinea-pig platelet activation assay. E: 1:10,000; WB: 1:1,000

Accession No.: P01024

Antigen: Human C3a (1)

Format: Each vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography.

Storage:
Store at 4°C. Product is guaranteed 6 months from the date of shipment.
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