C4 Complement (clone KT29), anti-human
€354.00
In stock
SKU
250123
Catalog Nr.: 250123
Size: 0.1 mg
Isotype: Mouse IgG1
Applications: E
Size: 0.1 mg
Isotype: Mouse IgG1
Applications: E
Protein Family: Enzymes
Pathway and Disease: Immune System
Description:
The complement component C4 plays a central role in the activation of the classical pathway of the complement system. C4 is cleaved by activated C1 which removes the C4a anaphylatoxin from the alpha chain. The remaining active C4b fragment becomes a subunit of the C3 convertase (C4b2a) and the C5 convertase (C3bC4b2a) enzymes of the classical complement pathway. The C4a anaphylatoxin is a mediator of local inflammatory process. The C4A6 allotype is totally deficient in hemolytic activity. This antibody recognizes the human complement C4 in ELISA.
Alternate Names: Complement C4-A, Acidic complement C4, C4 beta chain, C4-A alpha chain, C4a anaphylatoxin, C4b-A, C4d-A, C4 gamma chain, C4A, C4B, Basic complement C4, C4-B alpha chain, C4b-B, C4d-B
Application Notes: E: 1 ug/ml
Accession No.: P0C0L4, P0C0L5
Antigen: Purified human complement C4 protein
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Pathway and Disease: Immune System
Description:
The complement component C4 plays a central role in the activation of the classical pathway of the complement system. C4 is cleaved by activated C1 which removes the C4a anaphylatoxin from the alpha chain. The remaining active C4b fragment becomes a subunit of the C3 convertase (C4b2a) and the C5 convertase (C3bC4b2a) enzymes of the classical complement pathway. The C4a anaphylatoxin is a mediator of local inflammatory process. The C4A6 allotype is totally deficient in hemolytic activity. This antibody recognizes the human complement C4 in ELISA.
Alternate Names: Complement C4-A, Acidic complement C4, C4 beta chain, C4-A alpha chain, C4a anaphylatoxin, C4b-A, C4d-A, C4 gamma chain, C4A, C4B, Basic complement C4, C4-B alpha chain, C4b-B, C4d-B
Application Notes: E: 1 ug/ml
Accession No.: P0C0L4, P0C0L5
Antigen: Purified human complement C4 protein
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
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