Caspase-6 (N-term) polyclonal, anti-human, mouse, rat

Protein Family: Peptidases, Enzymes

Pathway and Disease: Cell Growth and Death, Neurodegenerative Disorders

Description:
Caspase-6 is involved in the activation cascade of caspases responsible for apoptosis execution. Caspase-6 is activated by cleavage by CPP32, caspase-8, or -10 which generates the two active subunits. Caspase-6 cleaves poly(ADP-ribose) polymerase in vitro as well as lamins.

Alternate Names: Caspase-6, CASP-6, Apoptotic protease Mch-2, Caspase-6 subunit p18, Caspase-6 subunit p11, CASP6, MCH2

Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:200-1:500

Accession No.: P55212

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human Caspase-6.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.