Caspase-6 polyclonal, anti-human

Protein Family: Peptidases, Enzymes

Pathway and Disease: Signal Transduction, Cell Growth and Death, Cancers

Description:
Caspase-6 is involved in the activation cascade of caspases responsible for apoptosis execution. Caspase-6 cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression of caspase-6 promotes programmed cell death. Caspase-6 is heterotetramer that consists of two anti-parallel arranged heterodimers, each one formed by a 18 kDa (p18) and a 11 kDa (p11) subunit.

Alternate Names: Caspase-6, CASP-6, Apoptotic protease Mch-2, CASP6, MCH2

Application Notes: E: 1:20,000-1:80,000; WB: 1:500-1:2,000

Accession No.: P55212

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human caspase-6.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.