Caspase-7 polyclonal, anti-human

Protein Family: Enzymes, Peptidases

Pathway and Disease: Cell Growth and Death, Neurodegenerative Disorders

Description:
Caspase-7 is involved in the activation cascade of caspases responsible for apoptosis execution. Caspase-7 cleaves and activates sterol regulatory element binding proteins (SREBPs). Caspase-7 proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Overexpression of caspase-7 promotes programmed cell death.

Alternate Names: Caspase-7, CASP-7, ICE-like apoptotic protease 3, ICE-LAP3, Apoptotic protease Mch-3, CMH-1, CASP7, MCH3

Application Notes: E: 1:1,000-1:100,000; WB: 1:100-1:500; IHC: 1:100-1:500; IF: 1:100-1:500

Accession No.: P55210

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within human caspase-7.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 2% BSA with 0.09% sodium azide. Antibody was purified by immunogen affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.