Caspase-9 (C-term) polyclonal, anti-human

Protein Family: Peptidases

Pathway and Disease: Signal Transduction, Cell Growth and Death, Cancers

Description:
Caspase-9 is known to be involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Caspase-9 proteolytically cleaves poly(ADP-ribose) polymerase (PARP).

Alternate Names: Caspase-9, CASP-9, ICE-like apoptotic protease 6, ICE-LAP6, Apoptotic protease Mch-6, Apoptotic protease-activating factor 3, APAF-3, Caspase-9 subunit p35, Caspase-9 subunit p10, CASP9, MCH6

Application Notes: E: 1:500-1:1,000; WB: 1:200-1:500; IHC: 1:200-1:500

Accession No.: P55211

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human Caspase-9.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 25% glycerol, 1 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.