Catenin beta-1 polyclonal, anti-human, mouse, rat
€362.00
In stock
SKU
251534
Catalog Nr.: 251534
Size: 0.1 mg
Isotype: Rabbit Ig
Applications: E, WB, IHC
Size: 0.1 mg
Isotype: Rabbit Ig
Applications: E, WB, IHC
Protein Family: Cytoskeleton Proteins
Pathway and Disease: Signaling Molecules and Interaction, Cell Communication, Immune System, Endocrine System, Cancers, Infectious Diseases
Description:
CTNNB1 (Catenin beta-1) is involved in the regulation of cell adhesion. The majority of catenin beta-1 is localized to the cell membrane and is part of E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton. Defects in catenin beta-1 are associated with colorectal cancer.
Alternate Names: Catenin beta-1, Beta-catenin, CTNNB1, CTNNB
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500
Accession No.: P35222
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human catenin beta-1.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 25% glycerol, 1 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Product Citations:
[1] Li MH et al. 2015. J Transl Med. 13: 271 PMID 26286725.
[2] Chen Y et al. 2011. International Journal of Surgical Pathology. 20(2): 189-193. PMID# 21791488.
Pathway and Disease: Signaling Molecules and Interaction, Cell Communication, Immune System, Endocrine System, Cancers, Infectious Diseases
Description:
CTNNB1 (Catenin beta-1) is involved in the regulation of cell adhesion. The majority of catenin beta-1 is localized to the cell membrane and is part of E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton. Defects in catenin beta-1 are associated with colorectal cancer.
Alternate Names: Catenin beta-1, Beta-catenin, CTNNB1, CTNNB
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500
Accession No.: P35222
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human catenin beta-1.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 25% glycerol, 1 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Product Citations:
[1] Li MH et al. 2015. J Transl Med. 13: 271 PMID 26286725.
[2] Chen Y et al. 2011. International Journal of Surgical Pathology. 20(2): 189-193. PMID# 21791488.
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