Catenin gamma (clone CN-3), anti-human, rat, chicken
€362.00
In stock
SKU
251719
Catalog Nr.: 251719
Size: 0.1 mg
Isotype: Mouse IgG1
Applications: E, WB, IHC
Size: 0.1 mg
Isotype: Mouse IgG1
Applications: E, WB, IHC
Protein Family: Cell Adhesion Molecules
Pathway and Disease: Cancers
Description:
Catenin gamma is junctional plaque protein. This membrane-associated protein is an architectural element and influences the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of catenin gamma in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. Defects in catenin gamma are the cause of Naxos disease (NXD). NXD is an autosomal recessive disorder combining diffuse non-epidermolytic palmoplantar keratoderma with arrhythmogenic right ventricular dysplasia/cardiomyopathy and woolly hair.
Alternate Names: Catenin gamma, Junction plakoglobin, Desmoplakin-3, Desmoplakin III, JUP, CTNNG, DP3
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500; ICC: 1:100-1:500
Accession No.: P14923
Antigen: Recombinant chicken catenin gamma.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 2% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Pathway and Disease: Cancers
Description:
Catenin gamma is junctional plaque protein. This membrane-associated protein is an architectural element and influences the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of catenin gamma in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. Defects in catenin gamma are the cause of Naxos disease (NXD). NXD is an autosomal recessive disorder combining diffuse non-epidermolytic palmoplantar keratoderma with arrhythmogenic right ventricular dysplasia/cardiomyopathy and woolly hair.
Alternate Names: Catenin gamma, Junction plakoglobin, Desmoplakin-3, Desmoplakin III, JUP, CTNNG, DP3
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500; ICC: 1:100-1:500
Accession No.: P14923
Antigen: Recombinant chicken catenin gamma.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 2% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
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