CD10 (clone 3G9D10), anti-human
€394.00
In stock
SKU
252809
Catalog Nr.: 252809
Size: 0.1 ml
Isotype: Mouse IgG1
Applications: WB, IHC
Size: 0.1 ml
Isotype: Mouse IgG1
Applications: WB, IHC
Protein Family: Cellular Antigens, Peptidases
Pathway and Disease: Immune System
Description:
CD10 is a 100kDa glycoprotein, also designated Common Acute Lymphocytic Leukemia Antigen (CALLA). It is a cell surface enzyme with neutral metalloendopeptidase activity which inactivates a variety of biologically active peptides. CD10 is expressed on the cells of lymphoblastic, Burkitt’s, and follicular germinal center lymphomas, and on cells from patients with chronic myelocytic leukemia (CML). It is also expressed on the surface of normal early lymphoid progenitor cells, immature B cells within adult bone marrow and germinal center B cells within lymphoid tissue. CD10 is also present on breast myoepithelial cells, bile canaliculi, fibroblasts, with especially high expression on the brush border of kidney and gut epithelial cells.
Alternate Names: Neprilysin, Neutral endopeptidase, NEP, Enkephalinase, Neutral endopeptidase 24.11, Atriopeptidase, Common acute lymphocytic leukemia antigen, CALLA, CD10 antigen, MME, EPN
Application Notes: WB: 1:500-1:2000; IHC: 1:200-1:1000
Accession No.: P08473; NP_009218
Antigen: Purified recombinant fragment of CD10 expressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Pathway and Disease: Immune System
Description:
CD10 is a 100kDa glycoprotein, also designated Common Acute Lymphocytic Leukemia Antigen (CALLA). It is a cell surface enzyme with neutral metalloendopeptidase activity which inactivates a variety of biologically active peptides. CD10 is expressed on the cells of lymphoblastic, Burkitt’s, and follicular germinal center lymphomas, and on cells from patients with chronic myelocytic leukemia (CML). It is also expressed on the surface of normal early lymphoid progenitor cells, immature B cells within adult bone marrow and germinal center B cells within lymphoid tissue. CD10 is also present on breast myoepithelial cells, bile canaliculi, fibroblasts, with especially high expression on the brush border of kidney and gut epithelial cells.
Alternate Names: Neprilysin, Neutral endopeptidase, NEP, Enkephalinase, Neutral endopeptidase 24.11, Atriopeptidase, Common acute lymphocytic leukemia antigen, CALLA, CD10 antigen, MME, EPN
Application Notes: WB: 1:500-1:2000; IHC: 1:200-1:1000
Accession No.: P08473; NP_009218
Antigen: Purified recombinant fragment of CD10 expressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
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