CD10 (clone HI10a), anti-human
€323.00
In stock
SKU
250943
Catalog Nr.: 250943
Size: 0.1 mg
Isotype: mouse IgG1
Applications: E, FC, IHC
Size: 0.1 mg
Isotype: mouse IgG1
Applications: E, FC, IHC
Protein Family: Cellular Antigens, Peptidases
Pathway and Disease: Immune System
Description:
The CD10 (HI10a) antibody recognizes neutral endopeptidase, a 100-kDa type-II transmembrane glycoprotein, which is referred as the Common Acute Lymphoblastic Leukemia Antigen (CALLA). CD10 antigen is expressed on a wide variety of normal and neoplastic cells including some subset of B and T lymphoid progenitors, germinal center cells, some granulocytes and fibroblasts. CD10 is a marker of common (pre-B) acute lymphocytic leukemias in which CD19, HLA-II and CD9 antigens are coexpressed. CD10 is a regulator of B cell growth and proliferation by hydrolysis of peptides having either proliferative or anti-proliferative functions.
Alternate Names: Neprilysin, Neutral endopeptidase, NEP, Enkephalinase, Neutral endopeptidase 24.11, Atriopeptidase, Common acute lymphocytic leukemia antigen, CALLA, CD10 antigen, MME, EPN
Application Notes: Purified antibody is suitable for immunohistochemistry with acetone-fixed frozen sections. E: 1:500-1:1,000; FC: 1:200-1:1,000; IHC: 1:200-1:500
Accession No.: P08473, NP_009218
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Product Citations:
Schlossman S. et al., eds. 1995. Leucocyte Typing V: White Cell Differentiation Antigens. P246, Oxford University Press, New York
Pathway and Disease: Immune System
Description:
The CD10 (HI10a) antibody recognizes neutral endopeptidase, a 100-kDa type-II transmembrane glycoprotein, which is referred as the Common Acute Lymphoblastic Leukemia Antigen (CALLA). CD10 antigen is expressed on a wide variety of normal and neoplastic cells including some subset of B and T lymphoid progenitors, germinal center cells, some granulocytes and fibroblasts. CD10 is a marker of common (pre-B) acute lymphocytic leukemias in which CD19, HLA-II and CD9 antigens are coexpressed. CD10 is a regulator of B cell growth and proliferation by hydrolysis of peptides having either proliferative or anti-proliferative functions.
Alternate Names: Neprilysin, Neutral endopeptidase, NEP, Enkephalinase, Neutral endopeptidase 24.11, Atriopeptidase, Common acute lymphocytic leukemia antigen, CALLA, CD10 antigen, MME, EPN
Application Notes: Purified antibody is suitable for immunohistochemistry with acetone-fixed frozen sections. E: 1:500-1:1,000; FC: 1:200-1:1,000; IHC: 1:200-1:500
Accession No.: P08473, NP_009218
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Product Citations:
Schlossman S. et al., eds. 1995. Leucocyte Typing V: White Cell Differentiation Antigens. P246, Oxford University Press, New York
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