CD117/c-Kit [clone EP10], anti-human

CD117/c-Kit [clone EP10], anti-human

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RM0067
Catalog Number: RM0067Clone: EP10Isotype: Rabbit IgGApplications: IHC
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Description: Member of the Tyrosine Kinase Receptor (TKRs) and highly homologous to receptor PDF and CSF-1. Activation of c-Kit tyrosine kinase by SCF (Stem Cell factor) leads to autophosphorylation and association of c-Kit with substrate PI3K. CD117 is a marker for Mast cell and gastrointerstinal stroma tumor. This anti-CD117 has been validated with excellent staining result by NordiQC, an independent scientific organization, promoting the quality of immunohistochemistry for pathology laboratories.Localization: membrane, cytoplasmDilution: 50-200Positive Control: lung adenocaHIER: citrate pH6.0 or EDTA pH8.0Status: RUO
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