CD117 (clone 104D2) PE-Cyanine7, anti-human RUO

This antibody reacts with the CD117 antigen, which is expressed within the haematopoeitic compartment on approximately 50 % of CD34+ progenitors engaged in erythrocytic, myelo-monocytic and megakaryocytic differentiation. The 104D2 monoclonal antibody reacts with human CD117, also known as c-Kit, Steel factor receptor and stem cell factor receptor. A member of the tyrosine kinase receptor family, this 145 kDa molecule is expressed by hematopoietic progenitor cell subsets and mast cells. The interaction of c-Kit and Steel factor promotes proliferation and differentiation of hematopoietic progenitor cells and mast cell differentiation.

Recomended usage
Immunostep’s CD117, clone 104D2 is a mAb intended for the identification of lymphoid progenitor. This reagent is effective for direct IF staining of human tissue for FCM analysis using ≤1 μg/10^6 cells.