CD11c (clone BU-15) APC, anti-human RUO

This antibody reacts with the CD11c antigen. Human CD11c (alpha X integrin) complexes with CD18 (beta2 integrin) to form the complement receptor type 4 (CR4) heterodimer which binds to fibrinogen and is involved with monocyte/granulocyte adhesion during inflammatory responses. CD11c expression is restricted to leukocytes mainly of myeloid lineage with highest expression on macrophages.

Recomended usage
CD11c, clone BU-15, is a mAb intended for the identification/enumeration of human leucocytes using FCM. This reagent is effective for direct IF staining of human tissue for FCM analysis using ≤1 μg/10^6 cells.