CD14 (clone 5A3), anti-human
€394.00
In stock
SKU
252612
Catalog Nr.: 252612
Size: 0.1 ml
Isotype: Mouse IgG1
Applications: E, WB, IHC, FC
Size: 0.1 ml
Isotype: Mouse IgG1
Applications: E, WB, IHC, FC
Protein Family: Cellular Antigens
Pathway and Disease: Immune System, Cancers, Infectious Diseases, Cell Motility, Signal Transduction
Description:
CD14 antigen is a GPI-linked glycoprotein with a molecular weight of 55kD. The CD14 antigen is expressed on cells of the myelomonocytic lineage including monocytes, macrophages and Langerhans cells. Low expression is observed on neutrophils and on human B cells. CD14 antigen is a receptor for bacterial lipopolysaccharide (LPS, endotoxin) and the lipopolysaccharide binding protein (LBP). LBP and CD14 antigen serves two physiological roles. These proteins act as opsonin and opsonic receptor, to promote the phagocytic uptake of bacteria or LPS coated particles by macrophages.
Alternate Names: Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein, Monocyte differentiation antigen CD14, urinary form, Monocyte fiferentiation antigen CD14, membrane-bound form, CD14
Application Notes: E: 1:5000; WB: 1: 500-1: 2,000; IHC: 1: 200-1: 400; FC: 1: 200-400
Accession No.: P08571, NP_000582
Antigen: Purified recombinant fragment of human CD14 expressed in E. coli.
Format: Each vial contains 0.1 ml IgG (0.4 mg/ml) of PBS pH7.4 with 0.03% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Pathway and Disease: Immune System, Cancers, Infectious Diseases, Cell Motility, Signal Transduction
Description:
CD14 antigen is a GPI-linked glycoprotein with a molecular weight of 55kD. The CD14 antigen is expressed on cells of the myelomonocytic lineage including monocytes, macrophages and Langerhans cells. Low expression is observed on neutrophils and on human B cells. CD14 antigen is a receptor for bacterial lipopolysaccharide (LPS, endotoxin) and the lipopolysaccharide binding protein (LBP). LBP and CD14 antigen serves two physiological roles. These proteins act as opsonin and opsonic receptor, to promote the phagocytic uptake of bacteria or LPS coated particles by macrophages.
Alternate Names: Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein, Monocyte differentiation antigen CD14, urinary form, Monocyte fiferentiation antigen CD14, membrane-bound form, CD14
Application Notes: E: 1:5000; WB: 1: 500-1: 2,000; IHC: 1: 200-1: 400; FC: 1: 200-400
Accession No.: P08571, NP_000582
Antigen: Purified recombinant fragment of human CD14 expressed in E. coli.
Format: Each vial contains 0.1 ml IgG (0.4 mg/ml) of PBS pH7.4 with 0.03% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
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